The University of Louisville is a public university in Louisville, Kentucky. The University offers 70 bachelor’s degrees, 78 master’s degrees, and 22 doctorate degrees. Among the many courses offered at the institution, below is a list of some of the hardest.
1. BE 450 – Biomaterials & Biocompatibility

This is an advanced course in bioengineering that discusses biomaterials and the clinical relevance of biomaterial performance. Students will have to learn very complex and technical concepts throughout the course. Students will also have to attend a series of lab sessions that are considered very engaging and time-consuming.
2. BIOL 485 – Microbial Physiology

This biology course discusses microbial cell biology and the processes, reactions, and energetics that support microbial life. Students find this course hard because it involves a lot of technical concepts and terminologies that need time to be familiar with. This course is recommended for students taking a major in Biology.
3. CIS 440 – Object-Oriented Methods

This course in computer information systems is considered hard by students because it discusses very complex and technical concepts related to the object-oriented paradigm. Students will need to allocate more study time in order to grasp the concepts and excel in exams.
4. CECS 310 – Discrete Structures

Computer Engineering and Computer Science courses are most likely than not considered difficult due to their technical nature. This course is no different as students will be required to study complex and technical concepts such as algebraic computational structures, finite state machines, relational structures, propositional logic, trees, and graphs among others.
5. CEE 450 – Geomechanics

This is an advanced course in civil and environmental engineering. Students get introduced to very complex concepts related to environmental engineering. Students will also have to engage in a series of very engaging practicals related to the main field of study.
6. CHEM 466 – Physical Chemistry II

This advanced course in chemistry discusses very technical and complex topics such as thermodynamics, statistical thermodynamics, chemical equilibrium, and reaction kinetics. Students will also be subjected to several lab sessions that will be very challenging and time-consuming.
7. PHYS 361 – Atmospheric Thermodynamics

Atmospheric thermodynamics is an advanced course in physics mostly recommended for physics majors. The course focuses on the principles of thermodynamics and their applications to atmospheric structure and dynamics. Students have a hard time internalizing the concepts and they need to allocate more study time to excel in exams.
8. MATH 405 – Differential Equations

Like most advanced math courses, differential equations is considered very hard. It focuses on methods and formulas that would find solutions for different types of differential equations. Students will be introduced to very complex mathematical formulas and theories that they are required to use to solve various mathematical problems.
9. ECE 420 – Signals and Linear Systems

This course in electrical and computer engineering is considered hard by most students because of the technical nature of the topics. Students will be introduced to very technical terminologies and concepts that are difficult to comprehend. Students will also be involved in a series of practical sessions that are equally technical before the end of the course.
10. GEOS 367 – Geomorphology

This course in the field of geosciences focuses on the study of the relationship between climate and tectonics to Earth-surface processes and the development of landforms and landscapes. It is a very technical course that involves complex concepts and a series of practical sessions.